Iron Replacement Formula:
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The Iron Replacement Formula calculates the required iron dose for patients with iron deficiency anemia. It considers body weight, target hemoglobin level, current hemoglobin level, and iron depot stores to determine the appropriate iron replacement dose.
The calculator uses the iron replacement formula:
Where:
Explanation: The formula calculates the iron deficit based on hemoglobin difference and body weight, then adds the required depot iron stores to determine the total iron replacement dose.
Details: Accurate iron dose calculation is crucial for effective treatment of iron deficiency anemia, preventing both under-treatment and iron overload, and optimizing patient outcomes.
Tips: Enter weight in kg, hemoglobin values in g/dL, and depot iron in mg. All values must be valid (weight > 0, hemoglobin values > 0, depot ≥ 0).
Q1: Why is the 2.4 factor used in the formula?
A: The factor 2.4 accounts for the iron content in hemoglobin and the efficiency of iron utilization during erythropoiesis.
Q2: What is a typical depot iron value?
A: Depot iron typically ranges from 500-1000 mg, representing iron stores in the liver, spleen, and bone marrow.
Q3: How often should iron levels be monitored during treatment?
A: Iron levels should be monitored every 4-6 weeks during iron replacement therapy to assess response and adjust dosing if needed.
Q4: Are there any contraindications for iron therapy?
A: Iron therapy should be used with caution in patients with hemochromatosis, chronic liver disease, or known hypersensitivity to iron preparations.
Q5: What are the common side effects of iron replacement?
A: Common side effects include gastrointestinal discomfort, constipation, nausea, and dark stools. Intravenous iron may cause infusion reactions.